Sunifiram (DM235) powder (314728-85-3) hplc≥98% – Nootropics Wisepowder

Sunifiram (DM235) powder (314728-85-3) hplc≥98% – Nootropics Wisepowder https://www.wisepowder.com/product-details/314728-85-3/ Chemical Base Information Name Sunifiram/DM235 CAS 314728-85-3 Purity 98% Chemical name 1-benzoyl-4-propanoylpiperazine Synonyms DM-235 Molecular Formula C14H18N2O2 Molecular Weight 246.304 g/mol Melting Point 57-58 °C InChI Key DGOWDUFJCINDGI-UHFFFAOYSA-N Form Solid Appearance…

Sunifiram (DM235) powder (314728-85-3) hplc≥98% - Nootropics Wisepowder

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Sunifiram (DM235) powder (314728-85-3) hplc≥98% – Nootropics Wisepowder

https://www.wisepowder.com/product-details/314728-85-3/

Chemical Base Information
Name Sunifiram/DM235
CAS 314728-85-3
Purity 98%
Chemical name 1-benzoyl-4-propanoylpiperazine
Synonyms DM-235
Molecular Formula C14H18N2O2
Molecular Weight 246.304 g/mol
Melting Point 57-58 °C
InChI Key DGOWDUFJCINDGI-UHFFFAOYSA-N
Form Solid
Appearance white crystalline powder
Half Life about 2-3 hours
Solubility Freely Soluble in Propylene Glycol, Soluble to 10 mM in Ethanol, Soluble to 5 mM in Water.
Storage Condition Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Application DM235 (Sunifiram) is a AMPAkine-like nootropic up to three orders of magnitude more potent than piracetam in animal studies.
Testing Document Available
03 Sunifiram (DM235) General Description
Sunifiram (DM-235) is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

04 Sunifiram (DM235) History
Sunifiram (DM-235) is an experimental research chemical derived from Piperazine that has potent anti-amnesia effects. It is often grouped with the racetam compounds but is technically not a racetam due to the broken pyrrolidone backbone.

Animal research has shown that it has a significantly greater potency than Piracetam or Phenylpiracetam. Sunifiram is related to Unifiram – it is a chemically simplified version of Unifram. Animal studies indicate that one key mode of action for Sunifiram is through interactions with the glutamergic system – particularly through AMPA-receptor activation. It is therefore considered an AMPAkine.

In 2006, researchers indicated that both Sunifiram and Unifiram were around four orders of magnitude more potent than Piracetam. Although the compounds did not show affinity for several important binding sites, they were found to prevent amnesia through modulation of various neurotransmitter systems and by increasing acetylcholine release in the cerebral cortex.

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